https://www.translationalchemistry.com/index.php/translationalchemistry/issue/feed 2025-12-05T15:44:56+00:00 Carlos Lodeiro Y Espiño clodeiro@bioscopegroup.org Open Journal Systems <div class="mainrow"> <div class="homeImageMini"> <p><strong>Translational chemistry</strong> refers to the application of fundamental chemical research to real-world problems, often bridging the gap between laboratory discoveries and practical applications in areas like medicine, biology, materials science, arts, engineering, pharmaceutics and environmental science. It emphasizes taking insights gained from basic chemistry, molecules and translating them into innovations, such as new drugs, new sustainable materials, or processes that can be used in technology, hospitals, and industry. This approach often involves collaboration across disciplines, integrating knowledge from chemistry, biology, engineering, and other scientific fields to drive progress and address complex challenges.</p> <p>For example, One crucial molecule in translational chemistry is adenosine triphosphate (ATP) and their relative ADP and AMP, which plays a vital role in cellular energy transfer. ATP serves as the primary energy currency in biological systems, driving numerous biochemical processes essential for life, such as muscle contraction, nerve impulse propagation, and biosynthesis.</p> <p>Its significance extends beyond basic biology; in translational chemistry, ATP's role in cellular metabolism has guided the development of targeted therapies for diseases like cancer., but also it is a very exciting molecule in the functionalization and preparation of gold and Silver nanoparticles. This connection between fundamental research on ATP and its translational applications in other fields, exemplifies how a single molecule can illuminate pathways to innovative treatments, materials, nanomaterials, that ultimately improving patient outcomes and advancing the field of medicine.</p> <p>Translational Chemistry is a multidisciplinary journal involving Chemistry in any scientific field.</p> <p><strong>Commitment on Diversity, Equity and Inclusion</strong></p> <p>Translational Chemistry – An Interface Journal has embraced integrity, transparency, inclusivity, collaboration, and freedom of thought as core values in its mission to evaluate, publish, disseminate, and enhance the scientific excellence of chemistry research from diverse global communities.</p> <p>Central to these values is the acknowledgment that achieving meaningful progress in diversity, equity, and inclusion—considering various identities and their intersections such as ethnicity, race, culture, nationality, gender, sexual orientation, age, disabilities, and socioeconomic status—is essential for the chemistry and broader scientific communities.</p> <p>Without this progress, they will be ill-equipped to address the challenges that lie ahead. The active participation of all community members is vital not only because evidence shows that diversity fosters innovation, improves decision-making, and enhances adaptability, but also from an ethical standpoint, ensuring that research benefits everyone, addresses global issues, and has the greatest possible impact.</p> </div> </div> https://www.translationalchemistry.com/index.php/translationalchemistry/article/view/246 2025-06-17T09:43:14+00:00 Carlos Lodeiro clodeiro@bioscopegroup.org Laura Mercolini laura.mercolini@unibo.it José Luis Capelo jlcm@fct.unl.pt 2025-07-14T00:00:00+00:00 Copyright (c) 2025 Translational Chemistry – An Interface Journal https://www.translationalchemistry.com/index.php/translationalchemistry/article/view/247 2025-11-11T12:02:37+00:00 Silvia Nuti silvia.nuti3@unibo.it Carlos Lodeiro clodeiro@bioscopegroup.org

<p style="font-weight: 400;">Metallic nanoparticles (NPs) exhibit size- and shape-dependent properties that have positioned them at the forefront of nanoscience and nanotechnology. Their synthesis spans top-down and bottom-up approaches, including direct, seed-mediated, and composite strategies, each offering distinct advantages and limitations. Understanding nucleation, growth, and stabilization processes is essential to control morphology and functionality, which in turn govern their optical, catalytic, and biological behaviours. This introductory review provides a didactic overview of metallic NPs synthesis, highlighting the connection between structure and properties. Integrating historical context, theoretical principles, and practical examples, this review outlines the key concepts linking the synthesis, structure, and behaviour of metallic NPs.</p>

2025-12-05T00:00:00+00:00 Copyright (c) 2025 Translational Chemistry – An Interface Journal https://www.translationalchemistry.com/index.php/translationalchemistry/article/view/248 2025-11-25T14:47:57+00:00 Beatriz Quintas br.quintas@campus.fct.unl.pt Joana Galhano j.galhano@campus.fct.unl.pt Elisabete Oliveira ej.oliveira@fct.unl.pt Hugo M. Santos hms14862@fct.unl.pt

<p>Proteinuria, the presence of elevated protein levels in urine, is an important biomarker associated with various diseases. This study presents a portable, smartphone-based approach for colourimetric protein detection using gold nanoparticles (AuNPs). By inducing the aggregation of AuNPs in the presence of albumin, facilitated by sodium chloride, distinct colour changes were observed and quantified<em> via</em> smartphone image analysis. The method was tested using three smartphone models on urine samples from six volunteers, demonstrating a detection limit of 1.19 μg/mL and the ability to visually detect protein concentrations as low as 25 μg/mL. Furthermore, we successfully quantified the urinary proteome of a CRC patient, obtaining a protein concentration of 37 ± 3 μg/mL, which closely agrees with the value of 41 ± 1 μg/mL determined by the Bradford assay. This technique offers a rapid, cost-effective, and non-invasive tool for urinary protein detection, with promising applications in routine clinical diagnostics and disease monitoring.</p>

2025-12-05T00:00:00+00:00 Copyright (c) 2025 Translational Chemistry – An Interface Journal https://www.translationalchemistry.com/index.php/translationalchemistry/article/view/249 2025-12-05T15:44:56+00:00 Inês F. Domingos ines.domingos@bioscopegroup.org

<p>Volume 1 Issue 2 (2025)</p>

2025-12-05T00:00:00+00:00 Copyright (c) 2025 Translational Chemistry – An Interface Journal